Monday, June 15, 2015

Fluoride: Friend or Foe?

In dental profession, the term "dental IQ" is used to describe one's knowledge about things/issues dental related. With the growing exposure of internet, social media, and health related television shows, our patients' dental IQ has grown tremendously. However, as their dental knowledge grows, so do their concerns: what kind of materials are being used, is it harmful to their body as a whole, is it better to treat it or leave it? One I have been getting from a lot of parents is safety of fluoride in our water system.

History

The Center of Disease Control and Prevention (CDC) proclaimed community water fluoridation as one of 10 great public health achievements of the 20th century. In 1945, Grand Rapids, Michigan became the first city in the world to calibrate the level of fluoride in its water supply to prevent tooth decay. In 1951, water fluoridation became an official policy in the U.S. and by 2012, 67.1% of U.S. population were getting fluoridate water from community water system (CWS) at or higher than recommended level. Studies have shown that occurrence of cavity has dropped significantly due to fluoridation of our water system.

Risks and Benefits

The good:

  • Regardless of method of fluoride exposure, it creates low level of fluoride ion in our saliva and plaque, which means its effect is topical (on the surface).
  • Fluoride "prevent" dental decay by controlling the rate which cavities develops instead of actively removing bacteria/cavities.
  • Fluoride ion forms a protective layer called fluorapatite which is:
    • more acid resistant (acid makes our teeth "soft") than hydroxyapatite, part of original composition of our teeth
    • forms quicker than remineralization of enamel - so our teeth "harden" faster
The bad:
  • Fluorosis is the only adverse effect of fluoride at recommended level. Its symptoms ranges from discoloration of the tooth (white to brown) to pitting of enamel. For specific categorization of severity of fluorosis, please refer to Dean's Index.
Photographs of Dental Fluorosis by Dr. Hardy Limeback and Dr. Iain Pretty, et al.
  • The critical period of exposure is from age of 1-4 (when teeth are forming) with risks ending at age of 8.
American Dental Association (ADA) has a risk assessment for kids from age of 0-6, when a patient falls into the high risk group, fluoride treatment is highly recommended.

Image from ADA.org

As you can see, fluoride exposure is only one of the assessments. If a patient has recommended fluoride exposure but still fall into high risk group, we will target treatment from other approach such as hygiene habit and diet.

What is the Safe Level?

According to ADA, the US Public Health Service's latest recommendation for optimal ratio of fluoride to water is 0.7 parts per million.  You might wonder: how much is that? It is like 1 inch in 23 miles, 1 minute in 1000 days, or 1 cent in $14,000.

Fluoride is present naturally in water and food as well, so when considering safe level of fluoridation, we also have to look into diet, toothpaste/mouthwash, medical/dental supplement as well.
  • FluorideAlert.org has a list of food containing fluoride and concentration of each item.
  • To understand specific concentration of fluoride in dental products, please go to ADA.org
How to Avoid Fluoride in Water

Since not everyone reading this blog needs or agrees with fluoride supplement/treatment, I have included some ways to avoid fluoridated water:

  • Filtration - fluoride can be filtered out of water by the following three methods: reverse osmosis, deionizers (which use ion-exchange resins), and activated alumina. Brita or Pur WILL NOT filter fluoride from water.
  • Spring water - most spring water sold over the counter contains very little fluoride level. However, some brands do carry water with higher fluoride level than others. When in doubt, call the phone number on the labels, most companies will have the information available.
  • Water distillation - water distillation will remove most, if not all, fluoride. There are water distillers that fit right on our counter top which will be more than enough for household usage.
This article is meant to be a quick and simplified explanation of fluoride and its association with cavity prevention. If you are interested in a more information on the science behind fluoridation, please visit ADA.org, Fluoridealert.org, CDC.gov. To find out the fluoride level in your water system, please contact your local water department.

Wednesday, June 3, 2015

Xylitol: a Savior of Sweet Tooth

The other day, a mother of my little patient asked me to help her deal with her son's sweet tooth. Her concern is as much as she watches his sugar consumption, she cannot be with him all the time.  I told her as long as he controls the frequency, he should be fine. Then I saw the mother's face and realized what 9 year old controls anything he does? I recommended xylitol.  She asked me what xylitol is, not able to come up with a more refined answer, I told her: it's a plant-base sugar substitute.  That got me thinking, what exactly is xylitol?  How can I explain plainly to the next patient that ask me the question?  I decided to do some research and this post is what I found out.

What is Xylitol?

My first encounter with xylitol is in my "dental cavity" class at University of Michigan, I still remember the school dental store being our only xylitol supplier. 10 years later, this sweetener is finally starting to get its fame in the United States. Xylitol is basically a sugar alcohol derived from mostly trees but can be found in some plants and fruits as well.  Here is what it looks like:

Xylitol Crystals

It looks just like sugar crystals, doesn't it?  How is it different from sugar?  Here is how:
  • It has 2.4 calories/gram vs. table sugar's 4 calories/gram.
  • Even though xylitol is a technically carbohydrate, it does not raise blood sugar level.  For that reason, it is not net carb hence a popular sweetener among low carb products.  
  • Its low glycemic index (12) also makes it a great sugar substitute for patients suffering from diabetes and metabolic syndromes.


How is xylitol good for our teeth?

The primary culprit of cavities is a particular kind of bacteria called S. Mutans.  It consumes sucrose (table sugar) and produces acid that causes our teeth to break down.  Because of the similar chemical structure of xylitol to sugar, it can be picked up but not digested by S. Mutans.  The bottom line is, xylitol can starve the harmful bacteria in the mouth, reducing plaque buildup and tooth decay. This can help prevent dental caries and inflammatory gum diseases.

For people who are interested in the scientific process of xylitol's anti-cavity function, here is a simplified list:

  • A molecule (tridentate ligand) in xylitol can rearrange with calcium and allows it to be transported through saliva and remineralize the outer layer of our teeth (enamel) before dental cavities form.  Basically, it prevents teeth from becoming "soft."
  • S. Mutans cannot digest xylitol, so once they pick up xylitol their sugar metabolism is blocked.  Without proper energy being released from the process, it eventually dies from "starvation."  No bacteria, no cavities.
  • Reduction of stomach acid normally created by sugar will decrease the degradation of enamel from erosion.


Where to get it?

Xylitol can be found in chewing gum, candies, and numerous dental products.  Here are some I have been recommending to my patients:
  • Chewing gums - Mentos Pure Fresh, Xlear Spry Gum, Glee Gum, 
  • Candy and sugar substitutes - Dr. John's Candies, Xylosweet by Xlear
  • Toothpaste - Tom's of Maine, Xlear Spry 
  • Mouthwash - Tom's of Maine, Xlear Spry
I have tried most of them. Dr John's have been particularly adept with convincing my smaller patients to be brave in the chair and their caramel and chocolate have rescued me from my own sweet cravings more than I would like to admit!  I haven't had a chance to experiment with a xylitol recipe on my baking weekends, but hope to do so in the future.  Leave me a comment if you have tried baking with any sugar substitute.

Xylitol is becoming increasingly accessible in these last few years and is likely to grow more and more in everyday use. There might be a day soon enough where cavities are no longer the infectious disease that is all too common and xylitol might just prove to be the tip of the iceberg that ends it.

Mentos Pure Fresh
Xlear Xylitol Products - Spry and Xylosweet
Tom's of Maine toothpaste
Dr. John'sThoughtfully Crafted Sweets